swiss medicaXXI century S.A.For the family of a four-year-old boy with cerebral palsy, some of the first changes they noticed after treatment appeared in small, everyday moments: taking steps without encouragement, offering his foot when shown his shoes, and leading his mother to the toys he wanted.
His mother shared these observations approximately two weeks after the family returned home from a nine-day program at Swiss Medica. The prescribed home program was still ongoing, and she emphasized that it was too early to draw firm conclusions.
Clinical Case · Patient overview
Before Treatment: The Boy’s Abilities and Main Challenges
The boy’s cerebral palsy was associated with extreme prematurity and a cerebral hemorrhage occurring around birth. Before his visit to Swiss Medica, his main support needs involved movement and communication:
- Mobility and muscle control. He had significant motor difficulties and muscle spasms and could not walk independently. Coordinating voluntary movements was challenging. He was receiving baclofen at night to help manage muscle tone.
- Spoken communication. He did not have functional spoken language and relied on other ways to express his needs.
- Non-verbal communication. One familiar way of making a request was to take his mother’s hand and lead her somewhere. Before treatment, she associated this behavior with his wish to go outside.
The family’s main goal was to support his overall motor abilities and help him gain more control over his movements.
Treatment at Swiss Medica
The boy attended a nine-day individualized program that included regenerative treatment, and an individual speech/occupational therapy.
Treatment Details
| Component | Administration described in the clinical record |
| SENSA Cells | Intravenous administration at approximately 0.5 million cells/kg |
| Allogeneic umbilical cord-derived MSCs | Intramuscular administration |
| Allogeneic placenta-derived MSCs | Intravenous administration at approximately 3 million cells/kg, plus 30 million cells intramuscularly |
| MSC-derived exosomes | Intravenous and intranasal administration |
| Autologous M2 macrophages | Included in the program |
| M2 macrophage secretome | Included in the program |
| Supportive therapy | An individual speech/occupational therapy session |
Following discharge, a five-week home program with M2 macrophage secretome and intranasal MSC-derived exosomes was prescribed.
Early Follow-Up: What Did His Mother Notice?
She emphasized that these were personal observations made during a very early follow-up period and that the family was not drawing definitive conclusions at this stage.
More Steps Without Encouragement
The most noticeable change was that the boy began taking spontaneous independent steps more frequently, without someone prompting him.
His mother also felt that he had better control over his body. She described an apparent improvement in his ability to carry out the movements he wanted to make.
These observations concerned individual steps and emerging movement control.
More Deliberate Vocal Sounds
His mother noticed that his vocalizations sounded more purposeful and included a wider range of vowel sounds.
She also thought she may have heard him say “yes” on a couple of occasions. She was careful to explain that this was uncertain and had not yet been established as a consistently used word.
Greater Engagement in Play and Daily Routines
The family described him as more focused, aware, and engaged with them.
During play, he began pointing to body parts. For example, he pointed to his mother’s mouth and prompted her to say “mouth.” In another everyday interaction, he deliberately offered his foot when shown his shoes.
For his family, these moments suggested greater understanding and more purposeful participation in familiar activities.
Clearer Non-Verbal Requests
His use of hand-leading also appeared to become more specific.
Previously, taking his mother by the hand had consistently signaled that he wanted to go outside. During the early follow-up period, he instead led her to the toy cupboard—something she reported he had never done before.
This gave his mother a clearer indication of what he wanted, extending a familiar way of communicating to a different request.
Continuing the Home Program
At the time of follow-up, the five-week home program was still ongoing. His mother reported that the boy tolerated the intranasal sprays well and that the prescribed home routine was manageable.
Overall Outcome
At approximately two weeks after returning home, the mother’s observations suggest early positive functional changes compared with the boy’s pre-treatment status, particularly in spontaneous stepping, purposeful vocalization, engagement and non-verbal communication.
These changes were reported while the five-week home program was still ongoing. The family regarded them as encouraging early observations, with more time needed to understand how consistently the emerging skills would appear in daily life.
Continued physiotherapy, occupational therapy and speech and language support remain important to help him develop these abilities and assess how they may contribute to greater everyday independence.