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Physician-Supervised Regenerative Medicine Protocols

Physician-Supervised Regenerative Medicine Protocols

We specialize in mesenchymal stem cell (MSC) therapy, exosome and secretome therapies, extracellular vesicles, and next-generation regenerative cell technologies. All cell-based products are produced, quality-controlled, and validated in our internal laboratory. Treatment programs also include diagnostics, rehabilitation, and physician follow-up within a comprehensive medical framework adapted to each patient’s diagnosis and condition.

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Physician-Supervised Regenerative Medicine Protocols
Since 2011 developing regenerative medicine protocols for neurological, autoimmune, degenerative, and age-related conditions.

Swiss Medica introduces SENSA Cells, the 6th generation of our MSC-based cell therapy products focused on optimizing the performance and durability of cell-based treatments

This increased resilience may help the cells survive and remain active for longer after administration, potentially enhancing the overall effectiveness of regenerative therapy.

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Swiss Medica introduces SENSA Cells, the 6th generation of our MSC-based cell therapy products focused on optimizing the performance and durability of cell-based treatments

How Treatment Protocols Are Adapted to Each Patient

Every patient comes to Swiss Medica with a different diagnosis, disease stage, symptom pattern, medical history, and treatment goal. For this reason, the protocol is adapted before the program begins and may be adjusted again after on-site diagnostics.

Our doctors consider the patient’s age, general health, previous therapies, laboratory findings, imaging results, functional goals, and contraindications. They also assess whether the patient is receiving stem cell therapy for the first time or returning for a follow-up program.

This approach helps the medical team choose the appropriate cell source, dosage, stem cell delivery methods, supportive therapies, rehabilitation plan, treatment duration, and follow-up strategy. Some patients may not qualify for treatment if the medical team determines that the risks are too high or the expected benefit is limited

How Cell Dose Is Calculated

Our program typically delivers up to 460 million units of cell-based therapy per program (extended programs include additional doses). The exact dose is calculated on a per-kilogram basis. Exosomes, secretome, and macrophage-based products may be used as supportive components for boosting stem cell therapy.

Exosomes are particularly useful here. They carry many of the same signaling molecules MSCs are released, but they are smaller, easier to deliver, and help “carry the effect” further after the cells have done their primary work.

~460M
Total cell-based therapy
78% 22%
~360M (78%)
Stem cells per program
~100M (22%)
Derivatives exosomes & more

Indicative figure based on Swiss Medica's program structure. The actual dose depends on the protocol, indication, body weight, and clinical response

Treatment Goals: Key Areas of Therapeutic Focus

Swiss Medica protocols are designed around several biological and clinical objectives intended to support recovery and symptom management, preserve function, and improve quality of life.

Modulate Immune Response

In some conditions, the immune system may become overactive or fail to respond appropriately. MSCs are studied for their immunomodulatory properties, meaning they may help support a more balanced immune response.

Reduce Systemic Inflammation

Chronic inflammation is involved in many neurological, autoimmune, degenerative, and difficult-to-treat conditions. Persistent inflammatory activity may contribute to pain, fatigue, tissue stress, immune imbalance, and slower recovery processes. MSC-based therapy is studied for its potential to help regulate inflammation.

Support Tissue Regeneration and Repair

MSCs release biologically active molecules that support communication between cells and tissue repair processes. This may be beneficial in conditions associated with tissue damage, degeneration, impaired mobility, nerve dysfunction, or slower recovery after injury. The goal is to create more favorable conditions for the body’s own recovery mechanisms.

Support Nervous System Repair and Protection

Many neurological conditions involve ongoing damage to nerve cells caused by inflammation, oxidative stress, and other biological processes. MSCs are being studied for their potential to support the cellular environment surrounding neurons and help protect nervous system tissues. This area of research is particularly relevant to conditions such as multiple sclerosis (MS), Parkinson's disease, ALS, stroke, and spinal cord injury.

What Patients Can Expect After Treatment

Regenerative effects often unfold gradually over weeks and months. Swiss Medica does not promise guaranteed results — we describe what is typically observed and supported by clinical experience.

1–3 months

Early response window

Early-stage improvements may appear: better sleep, improved mood, more stable energy, and reduced fatigue. The body begins integrating the regenerative signals delivered during the program.

3–6 months

Main response window

Inflammation modulation continues. Patients often describe their most observable changes here — reduced pain, better mobility, clearer speech, improved focus or behavior, better rehabilitation tolerance, and more stable clinical readings.

Long-term monitoring

Continued progress

Recovery and learning (for ASD patients) can progress more efficiently with rehabilitation and supportive care. Many patients consolidate gains, and some continue measurable improvement past the 6-month mark.

Results Across Treatment Programs

Symptom Improvements in Patients with ASD

93.4% Overall improvement rate of patients improved in at least one symptom after stem cell therapy
Social communication
90%
Hyperactivity & aggression
66.7%
Cognitive development
61.6%
Attention & focus
56%
Most reported:
Speech Eye contact Play Sleep & eating

Sources: collected testimonials and measurable patient-reported outcomes

Improvements in Patients with Multiple Sclerosis

68.8% Overall improvement rate of patients improved in at least one symptom after stem cell therapy
64.3%
improved Fatigue
53.3%
improved Muscle tone & motor
40%
improved Walking & balance
6-minute walk test 400 m » 507 m

Sources: collected testimonials and measurable patient-reported outcomes

Significant Improvements for Other Conditions

Motor control
61%
Daily independence
55%
Walking / balance
54%
Pain / stiffness
39%

Conditions where these improvements were reported:

ALS Parkinson's Spinal cord injury Arthritis & osteoarthritis Stroke Anti-aging & longevity Diabetes Eye disease / glaucoma
 Lung disease Liver disease

Sources: collected testimonials and measurable patient-reported outcomes

*

Results may vary depending on the individual condition, disease stage, medical history, and the protocol followed.

Autism

After the first treatment, we were shocked—Yuval started talking again. Within just a few weeks, he began looking into our eyes and saying ‘Mom’ and ‘Dad.’ From a nonverbal boy, he became a verbal boy. He is calmer now, understands tasks better, dresses himself after shower, communicates what he wants, and even started playing and cuddling with his younger brother. For our family, it wasn’t a small change—it changed our lives

Autism

We came with no big expectations — we just wanted to see if something could help our son. But even during the treatment days, we noticed things that surprised us: he went up to another child, said hello, and gave a handshake — something he had never done before. The next morning, he brushed his teeth by himself without constant reminders. The whole process was much easier than we expected, and the team made us feel safe and supported from the moment we arrived

Amyotrophic lateral sclerosis

Before treatment, I was afraid of losing my speech, swallowing, breathing, and facial control. My options in the U.S. felt extremely limited. After stem cell therapy, I noticed better facial muscle control, clearer speech and swallowing, improved breathing, and a real overall change within two months

Multiple sclerosis

My toilet urgency improved, my mobility became noticeably better, and I was able to walk without sticks again. For me, the most important change was that the disease progression felt more stable

Parkinson disease

I used to feel constantly tired and emotionally drained. After treatment, I had more energy, started smiling again, and felt more like myself. I could go out, spend time with friends, and enjoy ordinary daily activities

Spinal cord injuries

I was on heavy medication, taking multiple pills every day. After treatment, the pain steadily decreased until I was able to stop taking pain medication. I could stand and sit for longer, focus more at work, and walk slightly longer

Cell Products Used in Our Treatment Protocols

Stem cells used in therapy are selected to match the patient’s clinical needs.

Mesenchymal Stem Cells (MSCs)

The most extensively studied cell type in regenerative medicine. MSCs are valued for their immunomodulatory properties, paracrine signaling, and relatively low immunogenicity, which makes them well-suited for allogeneic applications. At Swiss Medica, MSCs form the backbone of most protocols — alone or in combination with cell-derived products such as exosomes and secretome.
Source Umbilical cord, adipose tissue, bone marrow, placenta
Mechanism Immunomodulation, paracrine signaling, tissue support
Applications Autoimmune, neurological, orthopedic, anti-aging
Why used Broadly studied, multi-system effect, well-tolerated

Exosomes

Extracellular vesicles released by MSCs. Exosomes carry many of the signaling molecules responsible for MSC effects — proteins, miRNAs, lipids — without the cells themselves. They are particularly useful when a protocol calls for extending the signaling effect after MSC administration, or when a less cell-dense delivery is clinically preferable.
Source Isolated vesicles from MSCs
Mechanism Cell-to-cell signaling, paracrine messaging
Applications Additional support, anti-inflammatory, anti-aging
Why used Smaller, easier delivery, complements cell therapy

Macrophages

Specialized immune cells that help regulate inflammation and support tissue repair. Often described as the body's "cleanup and coordination" cells, they remove damaged material and help guide healing processes. Used in selected protocols where targeted immune support is indicated.
Source Isolated cells from patient tissues
Mechanism Cell-to-cell signaling, paracrine messaging
Applications Additional support, anti-inflammatory, anti-aging
Why used Smaller, easier delivery, complements cell therapy

Secretome

The full mixture of bioactive molecules secreted by stem cells, including growth factors, cytokines, and exosomes. These substances help stem cells communicate with surrounding tissues and may support regeneration. Secretome-based products are used in some protocols to enhance these signaling effects.
Source MSC-conditioned media
Mechanism Paracrine support, growth factor delivery
Applications Additional support, anti-inflammatory, anti-aging
Why used Cell-free, sustained signaling effect

Stromal Vascular Fraction (SVF)

A cell-rich fraction isolated from adipose (fat) tissue. It contains MSCs, endothelial progenitor cells that support blood vessel formation, and other cell types that may contribute to tissue repair and recovery. Primarily used in protocols targeting joint disorders, diabetes-related complications, and certain eye conditions.
Source Patient's own adipose (fat) tissue
Mechanism Mixed regenerative signaling
Applications Orthopedic, diabetes, eye conditions
Why used Rich, autologous cell mix

Neural Progenitor Cells

Early-stage cells with the ability to develop into specialized nervous system cells. They are used in selected neurological protocols and may be considered when treatment goals focus on supporting nervous system function involving the brain, spinal cord, or peripheral nerves.
Source Patient-derived cells
Mechanism Neural lineage support
Applications Neurological conditions
Why used Neural-system targeted application

T-regulatory Cells (T-reg)

A type of immune cell that acts as one of the body's natural regulators, helping prevent the immune system from becoming overactive or attacking healthy tissues. T-reg cells may be used in selected protocols where targeted immune modulation is indicated.
Source Patient-derived / processed immune cells
Mechanism Immune balance regulation
Applications Conditions with chronic inflammation and autoimmune diseases
Why used Targeted immunological support

Natural Killer Cells (NK cells)

A type of immune cell that helps the body detect and eliminate abnormal cells. As part of the immune system's natural surveillance network, NK cells may be used in selected protocols where supporting immune surveillance function is a treatment goal. Natural killer cells are involved in immune surveillance.
Source Immune cell processing
Mechanism Immune surveillance
Applications Conditions with chronic inflammation and autoimmune diseases
Why used Supports innate immunity function

SENSA cells

A specialized, stress-resistant cell population developed by Swiss Medica. They are selected through a controlled stress-conditioning process designed to enrich for cells that can better withstand challenging environments such as inflammation, oxidative stress, and low oxygen levels. The goal is to increase the proportion of cells capable of remaining active after administration, particularly in damaged tissues where standard cells may be exposed to biological stress. SENSA Cells can be incorporated into selected regenerative medicine protocols, partially replacing standard MSCs.
Source Cell preparation using a controlled stress-conditioning technology
Mechanism Enhanced MSCs effects
Applications Autoimmune, neurological, orthopedic, anti-aging
Why used May support stronger functional activity in selected protocols

Official Dezawa MuseCells® Technology Available at Swiss Medica

Swiss Medica collaborates with Dezawa MuseCells® and can source officially licensed Dezawa cells upon patient request for use in selected treatment protocols. Muse cells are being studied for their ability to selectively home to sites of injury and contribute directly to tissue repair. This has made them a focus of research in areas such as stroke, spinal cord injury, and other complex regenerative medicine applications.

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Official Dezawa MuseCells® Technology Available at Swiss Medica

An Intensive 3–21-Day Regenerative Medicine Program

Depending on the condition being treated, programs typically last between 3 and 9 days (longer upon the patient's request). Accommodation, meals, daily care, and scheduled therapies are included, while our medical team provides 24/7 monitoring throughout the stay.

01

Initial Medical Evaluation

Before anything else, our medical team reviews the patient’s history, diagnostic data, and current symptoms to assess whether stem cell therapy is appropriate — and safe — for them.

Medical records review Symptom assessment Diagnostic analysis Eligibility screening Online consultation

If treatment risks outweigh the expected benefit, the patient may not be accepted for the program.

02

Personalized Protocol Design

After the medical review, the team prepares a treatment plan and a stem cell therapy cost estimate. While core treatment frameworks are well established, certain elements may be adapted to the patient’s condition, medical history, and treatment goals.

Treatment duration Cell type & source Dosage Administration route Supportive therapies

Autism treatment programs follow structured protocols based primarily on the duration of the patient’s stay at the clinic.

03

Arrival & On-Site Diagnostics

On arrival, the patient undergoes in-clinic diagnostics so that the protocol reflects their current condition — not just the data sent before travel. Alongside medical care, Swiss Medica helps coordinate travel arrangements and day-to-day support at the clinic.

Blood work Imaging Neurological assessment Functional testing Physician consultations Client care & support
04

Stem Cell Administration

Before administration, all biological products undergo a controlled laboratory pathway. The doctor selects the administration route according to the diagnosis, treatment goals, safety profile, and type of biological product. In some programs, several delivery methods may be combined to support systemic and local therapeutic goals.

IV infusion Intrathecal Intra-articular Intramuscular Local injections Nebulization Inhalation Topical applications Intranasal
05

Additional Procedures That Support Regeneration

Regenerative therapy works best when the biological part of the program is supported by a broader clinical plan. For this reason, supportive therapies are selected to help the patient’s body respond, recover, and maintain progress after the clinic stage.

IMR & drug therapie Medical devices therapies Peptide therapy Occupational therapy Speech therapy Massage & manual therapy Kinesiotherapy
06

Monitoring During Treatment

Treatment does not end with cell administration. Our medical team monitors patients throughout their stay, evaluates their response to therapy, and makes adjustments to the treatment plan when appropriate.

Physician supervision Symptom monitoring Protocol adjustments Progress tracking
07

Home Protocol

In some protocols, the home stage may continue for up to 5 weeks to help reinforce the biological activity initiated during the clinic program. The exact recommendations are selected individually by the physician.

Exosome or secretome therapy Rehabilitation guidance Remote follow-up
08

Free Follow-Up Check

A remote follow-up consultations are typically scheduled at 3 and 6 months to assess progress and treatment response. In addition, a complimentary follow-up clinic visit is included in treatment packages. The doctor may recommend:

Repeat treatment program Supportive rehabilitation course T-reg cell therapy Neural progenitor cell therap

Inside Our Lab: From Cell Source to Medical Release

  • Cell source confirmed donor-derived or patient-derived
  • Product prepared under controlled conditions in Swiss Medica's Europe-based GMP lab following established quality-control procedures for preparation and, storage.
  • Quality parameters checked microbiological screening and assessment of sterility, viability, and concentration
  • Clinical release before administration The final review of the prepared product before it is administered to the patient.

Cell Validation & Quality Assessment

Immune Compatibility of MSCs

Immune Compatibility of MSCs

A key consideration in any donor-derived cell therapy is how the cells interact with the recipient’s immune system. The characteristics below help explain why MSCs are commonly used in allogeneic regenerative medicine protocols.

01
Immune-modulating activity

MSCs influence immune signaling and help regulate immune responses through their immunomodulatory properties.

02
Low immunogenicity

MSC products express low levels of immune-recognition markers (MHC class II molecules). This may help reduce the likelihood that the body's immune defenses will react against the administered cells and limit their intended biological activity.

03
No Integration Into Patient DNA

MSCs do not become a permanent part of the patient's tissues or alter the patient's DNA. Their effects are believed to occur primarily through signaling molecules and interactions with surrounding cells rather than through genetic integration.

Sterility and Safety Assessment

Sterility and Safety Assessment

Sterility and safety assessment focus on reducing the risk of microbial contamination. This includes donor screening, controlled handling, microbiological checks, storage control, and final review before administration. This step is one of the key safety points in the Swiss Medica protocol. It helps ensure that the biological product used in treatment is traceable, properly handled, and suitable for the planned clinical application.

Cell Viability Testing

Cell Viability Testing

Cell viability testing measures the percentage of living cells within a prepared cell product before administration. High viability helps ensure that cells remain capable of carrying out their intended biological functions after treatment. As part of Swiss Medica’s quality-control procedures, cell products undergo viability assessment before clinical release. MSCs prepared in our GMP laboratory typically demonstrate viability rates of 95–98%.

Research-Informed Clinical Practice

Research-Informed Clinical Practice

We have developed a multidisciplinary medical and scientific team that includes specialists in neurology, cardiology, pediatrics, internal medicine, rehabilitation, laboratory medicine, and other fields. This broad clinical expertise supports the interpretation of emerging scientific research and its integration into patient care. Our treatment approaches continue to evolve through clinical observations and the analysis of patient outcomes as well. Swiss Medica supports this progress through its own ongoing research initiatives:

Our clinical study on  MSC therapy in ASD

Our clinical study on  MSC therapy MS

Start with a Free Medical Consultation

Our doctors will review your medical history and discuss possible treatment options. During the consultation, they will:
  • Answer your questions
  • Assess your suitability for regenerative therapies
  • Explain the treatment protocol, expected outcomes, and next steps
  • Provide a cost breakdown and explain pricing factors
Submitting the form does not mean starting treatment. It allows our medical advisers to determine whether further evaluation is appropriate.

* All cases are reviewed individually by medical professionals at our stem cell therapy center. Not all patients are eligible for regenerative therapies at a stem cell clinic.

FAQ

The protocol is determined after medical records review, symptom assessment, diagnostic analysis, eligibility screening, and physician consultation. These stem cell treatment steps help the medical team create a personalized plan based on the patient’s condition, safety profile, and treatment goals. The final plan may be adjusted after on-site diagnostics.
Swiss Medica uses established clinical protocols that are adapted to the patient’s diagnosis, condition, safety profile, and treatment goals. Each regenerative medicine protocol follows clinical principles but is adjusted individually.
The dose depends on diagnosis, body weight, treatment goals, safety profile, and administration method. In some protocols, the total cell-based therapy volume may include approximately 360 million cells together with derivative products, reaching around 460 million cell-based therapeutic units overall.
The best source depends on the patient’s condition and protocol. Swiss Medica may use donor-derived sources such as umbilical cord or placenta-derived tissues or patient-derived sources such as adipose tissue, bone marrow, or gingiva. The chosen source is part of the patient’s mesenchymal stem cell protocol when MSC-based therapy is included.
Program duration depends on the diagnosis and protocol complexity. Some programs may last several days in the clinic and continue with a structured home protocol after discharge.
Swiss Medica uses physician supervision, laboratory quality control, donor screening, viability testing, sterility assessment, and monitoring to support safety. These controls are especially important for patients looking for GMP stem cells in Europe and medically supervised regenerative treatment. Temporary side effects may occur, as with any medical procedure.
Some patients may not qualify if they have serious contraindications, unstable medical conditions, pregnancy, active infections, or certain cancer-related risks or if the medical team determines that treatment risks outweigh potential benefits.
Stem cells may be administered intravenously, intrathecally, intra-articularly, intramuscularly, locally, through nebulization, topically, or intranasally in selected protocols. When intravenous administration is used, the stem cell infusion procedure is performed under medical supervision.
Many procedures are generally well tolerated. Some injections or tissue collection procedures may involve temporary discomfort. Pain control or anesthesia may be used when needed.
Some patients report changes within weeks, while others notice gradual changes over several months. This reflects how stem cell therapy works in practice: response is usually individual and may depend on diagnosis, disease stage, treatment goals, rehabilitation, lifestyle, and individual biology.
The patient receives follow-up recommendations, home-care instructions, and supportive guidance when appropriate. This stage is part of what happens during stem cell therapy, because some protocols continue with a structured home stage after discharge.
Repeat treatment may be considered in some cases. The decision depends on diagnosis, response to the first program, disease progression, safety profile, and physician recommendation.

Selected Research & Clinical Reviews

MSC Safety

MSC Safety and Clinical Data Review

Stem Cell Research & Therapy (2021)

MSC Mechanisms

MSC Mechanisms and Clinical Evidence

Frontiers in Bioengineering & Biotechnology (2025)

Neurology

MSCs in Neurological Conditions (Review)

Frontiers in Medicine (2024)

Autism

MSC Therapy in Autism Spectrum Disorders

Frontiers in Cell & Developmental Biology (2022)

Autism

Cell-Based Therapies in Autism: Systematic Review

Middle East Current Psychiatry (2023)

Parkinson's

Mesenchymal Stem Cells in Parkinson's Disease

Frontiers in Cell & Developmental Biology / PMC (2021)

Amyotrophic lateral sclerosis

Cellular Therapy in ALS (featuring MSC research)

Frontiers in Cell & Developmental Biology

Stroke / TBI

MSCs for Stroke and Traumatic Brain Injury Recovery

PMC Review