facebook
+41 22 508 71 72
English

Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy

Lower back pain is a widespread issue that is not always recognized as a disorder. Every year, approximately 20% of Americans, including roughly half of working-age adults, report having back pain. According to statistics, 80% of adults will suffer from significant lower back pain at some point in their lives.

Lower back pain, often described as a persistent ache, sharp stabbing sensation, or radiating discomfort down the leg (sciatica), can severely limit daily activities, affecting everything from work productivity and exercise routines to simple pleasures like walking or sleeping comfortably. 

When it comes to recovery, you typically have two main options: pain medication and physical therapy for short-term relief, or surgery, which often involves recovery-related risks. However, these therapies frequently fail to address the underlying causes of lower back pain. That’s where stem cell therapy for lower back pain can help. This treatment aims to harness the body’s natural healing capabilities to repair damaged tissues, reduce inflammation, and ultimately alleviate pain. 

Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy
Radiating pain can be sharp or persistent, similar to an electrical shock or inner discomfort in the lower back. It may occasionally irradiate the pelvic area.

Here, we provide a comprehensive look at stem cell therapy for lower back pain, diving into the science of how it could regenerate various damaged tissues—including discs, nerves, and muscles—and improve their functions.

Common Causes of Lower Back Pain That Stem Cells Can Treat

Lower back pain refers to a variety of disorders affecting the vertebrae, muscles, nerves, and tendons in the area. Let’s delve into some common culprits.

Degenerative Disc Disease (DDD)

It is one of the most common conditions in which stem cells for lower back pain can be beneficial. Our intervertebral discs act as shock absorbers between the vertebrae, cushioning movement and providing flexibility. As we age, these discs can lose water content, becoming thinner and less resilient. This can lead to pain, stiffness, and spinal instability.

Herniated & Bulging Discs

Similar to degenerative disc disease, herniated and bulging discs involve problems with the intervertebral discs. 

A herniated discInvolves a tear in the outer layer (annulus fibrosus) of the disc, allowing the inner gel-like substance (nucleus pulposus) to protrude.
A bulging discOccurs when the disc extends beyond its normal space between the vertebrae, often due to age-related degeneration.

Both conditions can put pressure on nearby nerves, leading to sharp and radiating pain and muscle weakness.

Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy
Different types of intervertebral disc degeneration are characterized by targeted tissue that is unable to function properly. Stem cell therapy for chronic lower back pain can stimulate the body’s resources to regenerate tissue in this area.

Spinal Stenosis

Spinal stenosis is a narrowing of the spinal canal that squeezes the spinal cord and nerves. This can cause back pain, leg pain—numbness or tingling, and claudication—leg pain that worsens with walking and improves with rest.

Facet Joint Arthritis

Facet joints are small, stabilizing sockets located on the back of each vertebra. They support everyday movements and prevent you from twisting too much; they also can get arthritis or be injured from accidents or everyday wear and tear. Stem cell therapy for lower back arthritis can help to partially or fully restore facet joint function.

Chronic Inflammation & Muscular Pain

Chronic inflammation can cause lasting back and muscle pain from autoimmune diseases, infections, lifestyle, or myofascial pain. This leads to persistent aches, stiffness, limited movement, fatigue, and increased pain sensitivity.

Sciatica & Nerve Compression

Sciatica is not a condition but rather a symptom of a more serious issue caused by a compressed or irritated sciatic nerve that radiates pain down the leg from the lower back. Symptoms include sharp, electric-shock-like pain worsened by sitting or standing, plus numbness, tingling, and muscle weakness.

For each case of chronic lower back pain, stem cell therapy has the potential to significantly improve or impact traditional methods of recovery

What Is Stem Cell Therapy for Lower Back Pain?

Stem cell treatment for lower back pain is a regenerative medicine approach that utilizes the body’s own healing mechanisms to address the root causes of pain and slow the disease progression.

Does stem cell therapy work for lower back pain, one might wonder? According to recent studies and the way stem cells function, it does. Let’s see how stem cell treatment for lower back pain works in more detail.

How Stem Cells Help Regenerate Damaged Tissue

Stem cells are unique human cells that can help other tissues grow and repair themselves, ranging from muscle cells to brain cells. Here’s how stem cell transplants for lower back pain work: 

  1. After stem cells are introduced into the body, they circulate in the blood until they become attracted to proteins found around inflamed or damaged tissue
  2. Stem cells then rush to that injured area and start producing a potent cocktail of growth factors that stimulate cell growth and division:
  • Chemokines that guide other essential cells to the injury site,
  • Adhesion molecules that regulate crucial cell-to-cell interactions.

Using this multifaceted approach, stem cells for lower back pain promote regeneration of various tissue types by stimulating the growth of the microvascular network, which improves blood flow and nutrient delivery while also effectively reducing inflammation, thereby creating an environment for better recovery. 

Get a free online consultation

Contact our medical advisor today for a free, no-obligation consultation to learn more about how stem cell therapy can help your condition.

Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy
Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor


How Can Stem Cells Help with Lower Back Pain?

Stem cell therapy for the lower back may offer several potential benefits for patients.

Repairing Damaged Discs

By stimulating the regeneration of disc tissue, stem cell treatment for lower back pain can potentially restore cushioning and reduce pain associated with damaged intervertebral discs.

Reducing Inflammation Naturally

Stem cells possess anti-inflammatory properties, which can help mitigate chronic inflammation in the lower back, reducing pain and improving overall comfort.

Improving Mobility & Flexibility

Through pain reduction and inflammation processes, stem cell treatment for lower back pain can contribute to improved mobility and flexibility, enabling individuals to engage in daily activities with greater ease.

Types of Stem Cells Used in Back Pain Treatment

At Swiss Medica, we focus on using one particular type of stem cell for lower back pain: mesenchymal stromal cells, or MSCs. They can stimulate the growth of various cell types, most notably chondrocytes, which are essential for repairing damaged intervertebral discs. MSCs also have anti-inflammatory properties, which help to relieve pain while also supporting and speeding up the overall recovery process.

MSCs can be produced from a variety of tissue types:

Chronic lower back pain: stem cell sourcesTheir effect
Adipose-derived stem cells (from fat tissue)These MSCs, harvested from the patient’s own cells via a minimally invasive liposuction procedure, are abundant and provide a convenient source of stem cell therapy for the lower back.
Umbilical cord stem cellsCells that derived from voluntarily donated umbilical cords followed a healthy child’s birth. They are ethically obtained and have significant growth and differentiation potential.
Bone marrow stem cells (BMSC)These are harvested from the patient’s bone marrow, typically from the hip or lower back. 

After processing, these cells become bone marrow aspirate concentrate (BMAC), a concentrated stem cell and growth factor mixture that promotes recovery.

What to Expect from Stem Cell Therapy for Lower Back Pain?

It can take one to six months to see results after a stem cell injection in the lower back, and post-treatment rehabilitation might be recommended. Learn more about using stem cells to treat back pain in our dedicated article.

Benefits of stem cells for lower back painWhat does it mean?
It’s a minimally invasive treatmentThis procedure requires little to no downtime, making it a less invasive option than surgery.
Faster recovery for patientsStem cell therapy for lower back pain speeds recovery, allowing patients to resume normal activities sooner.
Long-term effectAfter receiving stem cell injections in the lower back, cells can remain active in the body for up to a year. Many patients report gradual symptom improvements within a few months.
Personalized treatmentAt Swiss Medica, we take a personalized approach to treatment, tailoring treatment strategies to individual patients based on their genetics, lifestyle, and overall health.

Who Can Benefit from Stem Cell Therapy for Lower Back Pain?

Individuals with chronic lower back pain who have not received satisfactory results from conventional treatments may be considered candidates for stem cell therapy. At Swiss Medica, we thoroughly evaluate all candidates to determine whether stem cells can help. It may necessitate additional tests by the patients.

Meet our patient who tried stem cell therapy for chronic back pain and share their experience in the video.

Stem Cells vs. Other Lower Back Pain Treatments

Stem cell therapy for lower back pain differs from conventional treatments by addressing the underlying causes of lower back pain through tissue regeneration, rather than solely managing symptoms. It may provide longer-term relief than some traditional approaches, such as those listed below:

  • Kinesiotherapy and massage
  • Rehabilitation
  • Medicine
  • Surgery

Patients see better results when these methods are combined with stem cell treatment. 

Is Stem Cell Therapy Safe for Lower Back Pain?

Stem cell therapy generally has a good safety record. No serious side effects are anticipated from the therapy; however, some patients may experience mild pain or discomfort following stem cell injections in the lower back, which will go away in a few hours. 

Choosing the Right Clinic for Stem Cell Therapy for Lower Back Pain

Selecting a reputable and qualified stem cell therapy clinic is paramount. Look for experienced medical professionals, positive patient testimonials, and a commitment to ethical practices and patient safety.

Swiss Medica, a stem cell clinic in Serbia, has been treating a wide range of conditions since 2011, including autoimmune disorders, chronic back pain, arthritis, and more. Over 10,000 people from all over the world have benefited from our care. We offer:

Personalized treatment plansAfter carefully reviewing your medical history, our regenerative specialists will devise a treatment plan that may involve stem cell therapy, other procedures, and follow-up care.
All-Inclusive careAll of our patients receive 24-hour medical attention, as well as nutritional meals prepared by our chef to meet your dietary requirements and a convenient transfer service that can meet you at Belgrade airport.
State-of-the-art facilitiesA beautiful main clinic with its own laboratory, a newly built hospital, and hotel-style accommodations for patients throughout their treatment program.
Own stem cell productionIn our in-house lab, we use and produce ethically sourced, high-quality stem cells while adhering to strict quality control.
Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy
Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy
Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy
Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy

Our newly opened Belgrade hospital provides cutting-edge medical care in a modern and comfortable setting.

Up to 80% of our patients experience significant improvements after stem cell therapy for lower back pain. You can explore our patient’s stories for yourself—we’ve got testimonials on YouTube talking about how these treatments have truly changed their lives.

How Much Does Stem Cell Therapy for Lower Back Pain Cost?

The cost of stem cell therapy varies according to the type of stem cells used, the treatment location, and the number of sessions required. 

Generally, stem cell therapy costs for the lower back pain can range anywhere from €10,000 to €50,000. The average cost of localized stem cell injections for the lower back ranges between €7,000 and €31,000*.

*The prices mentioned are indicative and subject to change based on individual factors, including the condition’s severity and the number of stem cells needed. Prices are valid as of January 2025.

Frequently Asked Questions About Stem Cell Therapy for Lower Back Pain

Contact us

Contact our medical advisor to discuss your health concerns and receive information about stem cell therapy, or leave your contact information for a callback. We will provide a free, no-obligation consultation to help you make an informed decision.

Stem Cell Therapy for Lower Back Pain: Symptoms, Causes, and Therapy
Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor


List of References

  1. Xie B, Chen S, Xu Y, Han W, Hu R, Chen M, He R, Ding S. Clinical Efficacy and Safety of Human Mesenchymal Stem Cell Therapy for Degenerative Disc Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Stem Cells Int. 2021 Sep 13;2021:9149315. doi.org/10.1155/2021/9149315

  2. Pers YM, Soler-Rich R, Vadalà G, Ferreira R, Duflos C, Picot MC, Herman F, Broussous S, Sánchez A, Noriega D, Ardura F, Alberca Zaballos M, García V, Gordillo Cano V, González-Vallinas M, Denaro V, Russo F, Guicheux J, Vilanova J, Orozco L, Meisel HJ, Alfonso M, Rannou F, Maugars Y, Berenbaum F, Barry FP, Tarte K, Louis-Plence P, Ferreira-Dos-Santos G, García-Sancho J, Jorgensen C; RESPINE consortium. Allogenic bone marrow-derived mesenchymal stromal cell-based therapy for patients with chronic low back pain: a prospective, multicentre, randomised placebo controlled trial (RESPINE study). Ann Rheum Dis. 2024 Oct 21;83(11):1572-1583. doi.org/10.1136/ard-2024-225771

  3. Manchikanti L, Knezevic E, Knezevic NN, Kaye AD, Atluri S, Sanapati MR, Pampati V, Hirsch JA. Effectiveness of Intradiscal Regenerative Medicine Therapies for Long-Term Relief of Chronic Low Back Pain: A Systematic Review and Meta-Analysis. Pain Physician. 2024 Dec;27(10):E995-E1032 https://pubmed.ncbi.nlm.nih.gov/39688822/

  4. Bartleson JD. Low Back Pain. Curr Treat Options Neurol. 2001 Mar;3(2):159-168. doi.org/10.1007/s11940-001-0051-4

  5. Martin BI, Tosteson ANA, Lurie JD, et al. Variation in the Care of Surgical Conditions: Spinal Stenosis: A Dartmouth Atlas of Health Care Series [Internet]. Lebanon (NH): The Dartmouth Institute for Health Policy and Clinical Practice; 2014 Oct 28. Back pain in the United States. Available from: https://www.ncbi.nlm.nih.gov/books/NBK586768/

More sources
Dr. Lana
Dr. Lana Reviewer

MD, Pediatrician, Regenerative Medicine Specialist

May interest you

Article
Video