Chronic obstructive pulmonary disease (COPD) is one of the most common medical conditions in the world today: research shows that nearly 5% of the population suffers from this disease.
According to 2016 World Health Organization estimates, COPD was the third leading cause of mortality worldwide.
A feature of the course of COPD is complications exacerbating the progression of the disease. This sooner or later leads to the development of respiratory dysfunction and further to a disability, significantly violating the quality of life of the patient, especially in case of frequent acute exacerbations.
There are a number of chemical-biological mechanisms that can influence the typical progressive nature of COPD. These mechanisms can be partially controlled by the methods of regenerative medicine which are being actively studied in connection with the therapy of pulmonary diseases.
How Do Stem Cells Work for COPD Treatment
Stem cells are immature cells that can proliferate and turn into adult cells in order to, for example, repair injuries. These cells have the ability to launch and maintain regenerative processes in damaged lung tissue, contributing to its recovery.
At the wound edge, cells differentiate and migrate to “cover up” the wounded area and release a variety of pro-inflammatory cytokines and growth factors to attract proteins and cells needed for the restoration of the extracellular matrix, which is crucial for normal wound repair. Once this occurs, re-epithelialization of the lung can proceed.
The anti-inflammatory and anti-fibrosis properties of stem cells make them particularly attractive as potential lung disease treatment.
Get a free online consultation to find out if stem cell treatment may work for you.
Clinical Results: What Improvements Do Patients Get?
In clinical practice, it was shown that stem cell therapy has good results. Multiple stem cell administration pathways (intravenous + inhalation) provide the optimum therapeutic effect. In particular, patients noted improvements such as:
- Respiratory and forced volume capacity increase.
- Rales and sputum production reduction.
- Reduction in frequency, strength, and duration of coughing episodes.
- Return of normal breathing & less frequent shortness of breath.
- Lung scar tissue reversal.
- Improved sleep quality.
- Increase in energy levels.
- Improved appetite.
- Cessation of chronic fatigue.
Watch Our Patient’s Results of COPD Stem Cell Treatment:
Patient from the USA (in English):
Patient from Italy (in Italian):
Improvements occur over a period of several weeks. For patients undergoing stem cell therapy, it is important to understand that more pronounced improvements can be achieved if a patient follows good respiratory practices in order to help injected stem cells do their best work. This includes potential changes in the patient’s lifestyle along with a healthy and nutritious diet combined with vitamin and mineral supplements.
Get a free online consultation to learn what results you can expect from stem cell treatment.
COPD Treatment with Stem Cells: The Procedure
At Swiss Medica Clinic, we employ cell products with a high number of viable stem cells (at least 80-90%) and use several application methods, including IV drip and inhalations. When using autologous (patient’s own) cells, the procedure includes separating the stem cells extracted from fat tissue or bone marrow. They are then activated and delivered intravenously directly back into the patient’s body within several hours.
Along with the adult autologous stem cells, we also use cell products created from donated tissues such as those harvested from the placenta or umbilical cord.
The quantity of restored cells is a therapeutic dose that not only covers daily losses of healthy cells in the patient but exceeds them a thousand times. Thus, the personal reserve of stem cells lost over the last 10–15 years is restored. It is because of this that cell therapy has a positive effect on overall health.
The procedure of stem cell therapy is very quick and simple. It does not require general anesthesia. Treatment is painless, does not bring discomfort and is completely safe even for elderly patients. All clinic treatments take place with round-the-clock doctor supervision.
Indications and Contraindications for Cell Therapy
Due to its benefits, therapy with stem cells can be promising in the absence or insufficiency of the effect of the main therapy, and also in the presence of side effects from the medical drugs.
- previous bad experience with cell products;
- any type of cancer or a precancerous condition;
- any life-threatening or terminal health conditions;
- infectious disease in the acute stage;
- stroke or transient ischemic attack in the last 3 months;
- deviations of some indicators in blood tests;
- pregnancy and lactation;
- mental disorders and addictions;
- contraindications to anesthesia and/or high risk of bleeding and/or pathological processes in the area of the proposed biopsy (does not exclude the possibility of using donor cell products),
- and some others.
Safety Issues & Side Effects
In most cases, there are no any side effects. Sometimes there may be a short-term increase in temperature as an individual reaction of the body, but not more than 2% of cases. And it passes independently and does not entail negative consequences for the patient’s health.
Stem cell therapy does not cause any allergic or immune reactions (due to the immune privilege status of multipotent MMSCs). It is also rejection free.
What the Treatment Includes
At Swiss Medica, we have developed treatment programs that are selected individually for each patient depending on their personal medical needs.
We provide stem cell lung regenerative therapy which is supported with optional additional treatment methods, such as:
- Ozone-laser injection therapy
- Xenon gas rehabilitation therapy
These therapies help to activate the regeneration process, restore mobility, and improve symptoms. This complex yet beneficial impact on the entire body.
We also provide doctor consultations (specialists in neurology, neurorehabilitation, psychology, and nutrition).
Get a free online consultation to learn what results you can expect from stem cell treatment, what the treatment program may include, and what the cost is.
Cumulative Statistical Report – COPD Cases
The goal of this report is to assess the success of stem cell treatment in chronic obstructive pulmonary disease patients at the Swiss Medica treatment center. Click on the picture to see the full report.
List of References
Can medicines development improve outcomes in asthma and chronic obstructive pulmonary disease management by driving effectiveness? David A. Leather, Louisa Yates, Henrik Svedsater, Loretta Jacques, Susan Collier, Danielle Powell & Rupert Jones. Respiratory Research. 2019 Aug 2;20(1):173.
Prognosis of COPD depends on severity of exacerbation history: A population-based analysis. Çolak Y., Afzal S., Marott J.L., Nordestgaard B.G., Vestbo J., Ingebrigtsen T.S., Lange P. Respiratory Medicine. 2019 Aug;155:141-147.
Stem Cells in Lung Injury and Repair. Felicia Chen and Alan Fine. The American Journal of Pathology. 2016 Oct; 186(10): 2544–2550.
Potential role of stem cells in management of COPD. Tillie L. Hackett, Darryl A. Knight, and Don D. Sin. International Journal of Chronic Obstructive Pulmonary Disease. 2010; 5: 81–88.
Stem cell therapy for lung fibrosis conditions. University of North Carolina Health Care. August 3, 2017.
Cell therapy for lung disease. Geiger S., Hirsch D., Hermann F.G. European Respiratory Review. 2017 Jun 28;26(144).
Medical Advisor, Swiss Medica doctor